Patrick Harrison


Cystic Fibrosis Gene Editing Group

The focus of the lab is to use CRISPR gene editing to correct CF causing mutations and explore routes to develop this for therapeutic application.

The lab is funded by Science Foundation Ireland, CF Trust (UK) and CF Foundation (USA), and currently has three post-docs and two PhD students.

We are currently working on Base Editing, Homology-Independent Targets Integration (HITI) Homology-Directed Repair (HDR) and Prime editing as outlined in recent publications – CRISPR for respiratory medicine (2022) – CF gene editing (2022) – Prime Editing (2021) – Base Editing and Disease (2019) – Gene Editing and Stem Cells (2018)

I also serve as European Editor for Gene Therapy

Patrick Harrison

Principal Investigator
Department of Physiology, School of Medicine 00353214901405


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University College Cork
Cork T12YT20


Areas of Expertise

  • Bioinformatics
  • Gene Therapy (non-viral)
  • Gene therapy (viral)
  • Training