Dr Piotr Kowalski (University College Cork) who leads a research group focused on developing novel, clinically relevant delivery technologies for nucleic acid-based therapies, speaks about exploring the potential of circular RNAs and how they could potentially address some of the limitations of current RNA vaccines and therapeutics.

The article for Vaccines Insights shares his findings on creating synthetic circular RNAs that show similar properties to linear mRNA, but can be more stable and less immunogenic, and potentially more sustainable to manufacture. More basic and translational research is required to fully harness the unique features and develop the therapeutic potential of this new class of RNA molecules, which is the topic of the ERC-funded work in Dr. Kowalski’s laboratory.  

Read the full article following the link below to learn about the therapeutic potential of circular RNAs.